“Include me if you can”—reasons for low enrollment of pediatric patients in a psychopharmacological trial

ConclusionsThe findings from this study add valuable information to the existing knowledge on reasons for low clinical trial recruitment rates in pediatric psychiatric populations. Low enrollment and high exclusion rates raise the question of whether such selective study populations are representative of clinical patient cohorts. Consequently, the generalizability of the results of such trials may be limited. The present findings will be useful in the development of improved recruitment strategies and may guide future research in establishing the measurement of representativeness to ensure enhanced external validity in psychopharmacological clinical trials in pediatric populations.Trial registrationEudraCT2014-003080-38. Registered on 14 July 2014.
Source: Trials - Category: Research Source Type: clinical trials