Microglia depletion by PLX3397 has no effect on cocaine-induced behavioral sensitization in male mice

In conclusion, while our data do not contradict previous findings indicating that different microglial-derived factors can have seemingly opposite effects on behaviors associated with cocaine use, they suggest that microglia do not have a net effect on cocaine-induced long-lasting behavioral changes.PMID:33639199 | DOI:10.1016/j.brainres.2021.147391
Source: Brain Research - Category: Neurology Authors: Source Type: research