Bedaquiline and Delamanid Safe Together Against Rifampicin-Resistant TB Bedaquiline and Delamanid Safe Together Against Rifampicin-Resistant TB

New research suggests concerns over the concurrent use of bedaquiline and delamanid in patients with drug-resistant tuberculosis were unwarranted.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Pulmonary Medicine News Source Type: news

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CONCLUSION: Since PJP often causes symptoms that are similar to other illnesses, such as the flu or tuberculosis, clinical and laboratory findings should be used simultaneously for making the final decision on drug administration.PMID:34557281 | PMC:PMC8421585 | DOI:10.18502/ijm.v13i4.6977
Source: Iranian Journal of Microbiology - Category: Microbiology Authors: Source Type: research
Phagosome-lysosome fusion in innate immune cells like macrophages and neutrophils marshal an essential role in eliminating intracellular microorganisms. In microbe-challenged macrophages, phagosome-lysosome fusion occurs 4 to 6 h after the phagocytic uptake of the microbe. However, live pathogenic mycobacteria hinder the transfer of phagosomes to lysosomes, up to 20 h post-phagocytic uptake. This period is required to evade pro-inflammatory response and upregulate the acid-stress tolerant proteins. The exact sequence of events through which mycobacteria retards phagolysosome formation remains an enigma. The macro...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
CONCLUSIONS: Correcting for miscoding and misclassification of cause of death data can enhance the utility of the data for analyzing trends in HIV mortality and tracking progress toward the Sustainable Development Goal targets.PMID:34546661 | DOI:10.1002/jia2.25791
Source: Journal of the International AIDS Society - Category: Infectious Diseases Authors: Source Type: research
This study aimed to assess the effect of isoniazid preventive therapy on the incidence of tuberculosis for seropositive children in Northwest Ethiopia. Methods. A facility-based retrospective follow-up was employed for reviewing 421 files from 1 January 2015 up to 30 December 2019. EpiData version 3.2 and Stata/14 software were used for data entry and analysis, respectively. Categorical variables at bivariable Cox regression were assessed for candidates transferred at P value
Source: Journal of Tropical Medicine - Category: Tropical Medicine Authors: Source Type: research
CONCLUSIONS: Correcting for miscoding and misclassification of cause of death data can enhance the utility of the data for analyzing trends in HIV mortality and tracking progress toward the Sustainable Development Goal targets.PMID:34546661 | DOI:10.1002/jia2.25791
Source: Journal of the International AIDS Society - Category: Infectious Diseases Authors: Source Type: research
This study aimed to assess the effect of isoniazid preventive therapy on the incidence of tuberculosis for seropositive children in Northwest Ethiopia. Methods. A facility-based retrospective follow-up was employed for reviewing 421 files from 1 January 2015 up to 30 December 2019. EpiData version 3.2 and Stata/14 software were used for data entry and analysis, respectively. Categorical variables at bivariable Cox regression were assessed for candidates transferred at P value
Source: Journal of Tropical Medicine - Category: Tropical Medicine Authors: Source Type: research
The creation of the Global Fund to Fight AIDS, Tuberculosis and Malaria, also known as the Global Fund, was prompted by the lack of a timely and effective global response, and the need for financing to fight a...
Source: Globalization and Health - Category: International Medicine & Public Health Authors: Tags: Research Source Type: research
Curr Top Med Chem. 2021 Sep 16. doi: 10.2174/1568026621666210916170417. Online ahead of print.ABSTRACTInfectious diseases have been evolving and re-evolving over the ages and causing immense misery to humans. Among them, some have been prevented and eradicated, but few are still threatening the modern era since their origin. The majority of these infectious diseases are poverty-driven, hence highly prevalent in the lower-income and mid-income countries of Africa and Asia. The world's deadliest infections, including Tuberculosis, Malaria and HIV/AIDS, have been considered as the "Big Three" infectious diseases (BT...
Source: Topics in HIV Medicine - Category: Infectious Diseases Authors: Source Type: research
Hundreds of thousands of people will die of tuberculosis left untreated because of disruption to healthcare systems in poor countries caused by the COVID-19 pandemic, a global aid fund said.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news
Source: Therapeutics and Clinical Risk Management - Category: Drugs & Pharmacology Tags: HIV/AIDS - Research and Palliative Care Source Type: research
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