Cyanoalkylation/alkynylation of allylic alcohol through intramolecular radical 1,2-alkynyl migration

Org. Biomol. Chem., 2021, Advance Article DOI: 10.1039/D1OB00192B, CommunicationShengnan Jin, Fan Chen, Pengcheng Qian, Jiang Cheng A di-tert-butyl peroxide (DTBP)-promoted difunctionalization of α-aryl α-alkynyl allylic alcohols with alkyl nitriles was developed, affording a series of α-alkynyl γ-cyano functionalized ketones in moderate yields. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - March 1, 2021 Category: Molecular Biology Authors: Shengnan Jin Source Type: research