Certainty of evidence and intervention's benefits & harms are key determinants of guidelines ’ recommendations

Development of trustworthy clinical practice guidelines (CPG) represents an important tool for improving clinical decision-making and optimizing patient outcomes.1-3,4,5 Although standards for producing trustworthy CPGs rest on methodological principles developed in evidence-based health care (EBHC) fields, 1,6 –8 CPGs’ trustworthiness ultimately depends on how guideline panel members exercise their individual and collective expertise to formulate recommendations. 9–11

Source: Journal of Clinical Epidemiology - March 1, 2021 Category: Epidemiology Authors: Benjamin Djulbegovic, Iztok Hozo, Shelly-Anne Li, Marianne Razavi, Adam Cuker, Gordon Guyatt Source Type: research