UKCTOCS update: applying insights of delayed effects in cancer screening trials to the long-term follow-up mortality analysis

ConclusionsThe decision to alter the follow-up analysis for the primary outcome on the basis of new evidence and using new statistical methodology for long-term follow-up is novel and has implications beyond UKCTOCS. There is an urgent need for consensus building on how best to design, test, estimate and report mortality outcomes from long-term randomised cancer screening trials.Trial registrationISRCTN22488978. Registered on 6 April 2000.
Source: Trials - Category: Research Source Type: clinical trials