Manganese-catalyzed Electro-oxidative Azidation-annulation Cascade to Access Oxindoles and Quinolinones

Chem Asian J. 2021 Feb 26. doi: 10.1002/asia.202100121. Online ahead of print.ABSTRACTAn environmentally benign and proficient electro-oxidative tandem azidation-radical cyclization strategy is reported. Manganese catalyzed electrochemical reaction in an undivided cell under room temperature and the use of NaN 3 as the cheapest azide source are the key features of this protocol. Using this approach, a series of oxindole and quinolinone derivatives are synthesized in high yields. The synthesized azide functionality was efficiently converted to various valuable derivatives.PMID:33636034 | DOI:10.1002/asia.202100121
Source: Chemistry, an Asian Journal - Category: Chemistry Authors: Source Type: research