Towards guidelines for time-trend reviews examining temporal variability in human biomonitoring data of pollutants

In this study, we therefore present a proposal for guidelines to conduct "time-trend reviews" (TTRs) that examine time trends in published large HBM datasets of chemical pollutant concentrations. We also demonstrate the applicability of these guidelines through a case study that assesses time-trends in global and regional HBM data on mercury. The recommended TTR guidelines in this study are divided into seven steps: formulating the objective of the TTR, setting up of eligibility criteria, defining search strategy and screening of literature, screening results of search, extracting data, analysing data, and assessing certainty, including the potential for bias in the evidence base. The TTR guidelines proposed in this study are straightforward and less complex than those for conducting systematic reviews assessing datasets on potential human health effects of exposure to pollutants or medical interventions. These proposed guidelines are intended to enable the credible, transparent, and reproducible conduct of TTRs.PMID:33626456 | DOI:10.1016/j.envint.2021.106437
Source: Environment International - Category: Environmental Health Authors: Source Type: research