Ring-fused dimethoxybenzimidazole-benzimidazolequinone (DMBBQ): tunable halogenation and quinone formation using NaX/Oxone

This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Darren Conboy, Patrick Kielty, Joseph C Bear, Jeremy Karl Cockcroft, Pau Farras Costa, Patrick McArdle, Richard Singer, Dennis Smith, Fawaz Aldabbagh Ring-fused benzimidazolequinones are well-known anti-tumour agents, but dimeric ring-fused adducts are new. The alicyclic [1,2-a] ring-fused dimethoxybenzimidazole-benzimidazolequinone (DMBBQ) intermediate allows late-stage functionalization of bis-p-benzimidazolequinones. DMBBQs are chlorinated and brominated at... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research