GSE166794 FOXO1 mitigates the SMAD3/FOXL2C134W transcriptomic effect in a model of human adult granulosa cell tumor

Contributors : Christian Secchi ; Paola Benaglio ; Francesca Mulas ; Martina Belli ; Dwayne Stupack ; Shunichi ShimasakiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGranulosa cell tumors (GCTs) are a rare form of stromal cell malignant cancer accounting for one in twenty cases of ovarian cancer. More than 400 tumors from aGCT patients of diverse ethnicities showed one single mutation in the Forkhead box L2 transcription factor gene FOXL2: Cys134Trp (c.402C

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE166794

Source: GEO: Gene Expression Omnibus - February 26, 2021 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research