Development of patient-specific 3D models from histopathological samples for applications in radiation therapy

The biological effect of ionizing irradiation on living tissues is typically quantified through the physical quantity of absorbed dose. While absorbed dose is correlated with biological outcomes it does not uniquely determine the biological effectiveness of an irradiation. In radiation therapy, knowledge of cancer pathology, local oxygenation, radiation quality, and numerous other factors are required to determine the relationship between absorbed dose and a biological outcome such as tumor control probability [1,2].
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Original paper Source Type: research