Degradation of ofloxacin by a manganese-oxidizing bacterium Pseudomonas sp. F2 and its biogenic manganese oxides

Bioresour Technol. 2021 Feb 14;328:124826. doi: 10.1016/j.biortech.2021.124826. Online ahead of print.ABSTRACTFluoroquinolone antibiotics like ofloxacin (OFL) have been frequently detected in the aquatic environment. Recently manganese-oxidizing bacteria (MOB) have attracted research efforts on the degradation of recalcitrant pollutants with the aid of their biogenic manganese oxides (BioMnOx). Herein, the degradation of OFL with a strain of MOB (Pseudomonas sp. F2) was investigated for the first time. It was found that the bacteria can degrade up to 100% of 5 μg/L OFL. BioMnOx and Mn(III) intermediates significantly contributed to the degradation. Moreover, the degradation was clearly declined when the microbial activity was inactivated by heat or ethanol, indicating the importance of bioactivity. Possible transformation products of OFL were identified by HPLC-MS and the degradation pathway was proposed. In addition, the toxicity of OFL was reduced by 66% after the degradation.PMID:33631461 | DOI:10.1016/j.biortech.2021.124826

Source: Bioresource Technology - February 25, 2021 Category: Biotechnology Authors: Kangjie Li Anlin Xu Donghong Wu Siyan Zhao Tong Meng Yongjun Zhang Source Type: research