Pregnancy and neonatal outcomes of COVID-19: co-reporting of common outcomes from PAN-COVID and AAP SONPM registries

CONCLUSIONS: The findings from the UK and US registries of pregnancies with SARS-CoV-2 infection were remarkably concordant. Preterm delivery affected a higher proportion of women than expected based on historical and contemporaneous national data. The proportions of pregnancies affected by stillbirth, a small for gestational age infant or early neonatal death were comparable to those in historical and contemporaneous UK and US data. Although maternal death was uncommon, the rate was higher than expected based on UK and US population data, which is likely explained by under-ascertainment of women affected by milder or asymptomatic infection in pregnancy in the PAN-COVID study although not in the AAP SONPM study. The data presented support strong guidance for enhanced precautions to prevent SARS-CoV-2 infection in pregnancy, particularly in the context of increased risks of preterm delivery and maternal mortality, and for priority vaccination of women planning pregnancy. This article is protected by copyright. All rights reserved.PMID:33620113 | DOI:10.1002/uog.23619

Source: The Ultrasound Review of Obstetrics and Gynecology - February 23, 2021 Category: Radiology Authors: Edward Mullins Mark L Hudak Jayanta Banerjee Trace Getzlaff Julia Townson Kim Barnette Rebecca Playle Tom Bourne Christoph Lees PAN-COVID investigators and the National Perinatal COVID-19 Registry Study Group Source Type: research