Circulating Wnt Ligands Activate the Wnt Signaling Pathway in Mature Erythrocytes

CONCLUSIONS: These findings provide evidence for intracellular signaling activity in enucleated cells and signal transduction in the blood circulation and thus open new and exciting avenues for studying the function of signaling pathways in the bloodstream.PMID:33626913 | DOI:10.1161/ATVBAHA.120.315413

Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 25, 2021 Category: Cardiology Authors: Ronen Siman-Tov Natalie Zelikson Michal Caspi Yakir Levi Chava Perry Fayhaa Khair Hagit Stauber Josu é Sznitman Rina Rosin-Arbesfeld Source Type: research