TERT Promoter Mutation in Adult Glioblastomas: It & #39;s Correlation with Other Relevant Molecular Markers

Conclusions: 43.5% of the GBMs showed pTERT mutation (C228T was commonest; 72%). pTERT mutations were mutually exclusive with ATRX protein loss, more commonly associated with IDH wild type and EGFR amplified GBMs.

Source: Neurology India - February 24, 2021 Category: Neurology Authors: Mukesh Barange Sridhar Epari Mamta Gurav Omshree Shetty Ayushi Sahay Prakash Shetty Jayantsastri Goda Aliasagar Moyiadi Tejpal Gupta Rakesh Jalali Source Type: research