Sensitivity to Sweets Tied to Weight Loss After Bariatric Surgery Sensitivity to Sweets Tied to Weight Loss After Bariatric Surgery
' We showed, for the first time, that preoperative sweet [taste] intensity predicts [greater] weight loss after surgery,'but surprisingly, hedonic hunger foretold the opposite, said a study author.Medscape Medical News
Conditions: Diabetes; Bariatric Surgery; Metformin Interventions: Drug: Metformin; Other: Standard Care Sponsors: Assistance Publique - Hôpitaux de Paris; Ministry of Health, France Not yet recruiting
k G Abstract As of October 2020, the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), responsible for Coronavirus Disease 2019 (COVID-19), has infected over 33million individuals and killed over one million people worldwide. (https://coronavirus.jhu.edu/map.html accessed October 1 2020) Obesity and its complications are linked to severe forms of COVID-19, favouring an increased hospitalization and mortality rate. Despite being the gold-standard for the treatment of selected individuals with severe obesity, there is scarce information on whether or not bariatric surgery modifies the prognosis of people...
Insulin resistance (IR) is one of the causes of type II diabetes mellitus (T2DM) in severely obese subjects. IR can be assessed by measuring the triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-c ratio) as well as by estimating the triglyceride to glucose index (TyG index). The aim of this study was to demonstrate the impact of rapid weight loss after bariatric surgery (BaS) on insulin resistance, and its relationship with better glycemic control in severely obese subjects with T2DM.
It is estimated that 71% of all newly diagnosed primary liver cancer cases in America are potentially preventable. Leading risk factors linked to its occurrence are alcohol abuse, obesity, and diabetes. The primary objective of our study is to determine the impact of bariatric surgery (BaSurg) on the probability of developing liver cancer and define the primary risk factors in a severely obese patient population.
Roux-en-Y gastric bypass (RYGB) affords a long-term, durable approach to the management of diabetes mellitus (DM) in morbidly obese patients. Nevertheless, patients with DM are at an increased risk for 30-day wound events and additional morbidity and mortality compared with patients without DM. The purpose of our study was to determine if there is a preoperative glycosylated hemoglobin (HgA1c) target level that can be used as a surrogate for optimization of DM in diabetic patients before RYGB.
This study characterizes changes in the microbiome and metabolome associated with improved metabolic control in NHPs undergoing VSG.
Obesity-related inflammation contributes to the pathogenesis of type 2 diabetes mellitus (T2DM). Galantamine activates the vagal-mediated cholinergic anti-inflammatory pathway (CAP). We hypothesize that galantamine will decrease food intake, body weight and improve glycemic control in the obese (db/db) mouse model.
Sleeve gastrectomy (SG) leads to rapid and sustained diabetes remission, and post-SG improvement in immune function has been implicated as a potential contributing pathway. Further, previous works have found mitochondrial and metabolic dysfunction contribute to insulin resistance. Here, we hypothesize that post-SG glycemic improvement is associated with enhanced B-cell metabolism and increased anti-inflammatory function.
The objective of this study was to examine the comparative effects of sleeve gastrectomy and Roux-en-Y gastric bypass (RYGB) on OOP spending after bariatric surgical procedures.
Postoperative hyperglycemia after cardiac surgery increases complications; however, there are no data regarding the duration of stress-induced hyperglycemia nor the impact of carbohydrate loading in cardiac surgery patients. Prior work in colorectal and bariatric surgery has shown a significant reduction in glycemic events with the use of a low dose maltodextrin and citrulline loading strategy. The aim of this study was to compare standard of care (SOC group) vs carbohydrate loading (CL group) on the duration and severity of postoperative hyperglycemia in both diabetic and nondiabetic cardiac surgery patients.