Repeated preoperative intranasal administration of insulin decreases the incidence of postoperative delirium in elderly patients undergoing laparoscopic radical gastrointestinal surgery: a randomized, placebo-controlled, double-blinded clinical study

Postoperative delirium (POD) is an acute neuropsychiatric syndrome that generally occurs within 7 days after surgery in elderly patients. The incidence of POD in elderly patients has been reported to be as high as 15% to 62%1. The development of POD not only increases mortality at 6 to 12 months after surgery but can also seriously affect quality of life and health status, prolong the length of hospital stays, increase hospitalization costs, and exert great pressure on society and families2, 3. In the United States, the 1-year health care costs associated with delirium in the elderly population have been estimated to exceed $38 billion4.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Regular Research Article Source Type: research