Nondisplaceable Binding Is a Potential Confounding Factor in 11C-PBR28 Translocator Protein PET Studies

Conclusion: Our findings suggest that in TSPO PET studies, nondisplaceable binding can differ between patient groups and conditions and should therefore be considered.

Source: Journal of Nuclear Medicine - February 23, 2021 Category: Nuclear Medicine Authors: Laurell, G. L., Plaven-Sigray, P., Jucaite, A., Varrone, A., Cosgrove, K. P., Svarer, C., Knudsen, G. M., Karolinska Schizophrenia Project Consortium, Ogden, R. T., Zanderigo, F., Cervenka, S., Hillmer, A. T., Schain, M. Tags: Clinical Source Type: research