Genes, Vol. 12, Pages 317: Investigating the Adoption of Clinical Genomics in Australia. An Implementation Science Case Study

Genes, Vol. 12, Pages 317: Investigating the Adoption of Clinical Genomics in Australia. An Implementation Science Case Study Genes doi: 10.3390/genes12020317 Authors: Stephanie Best Janet C. Long Clara Gaff Jeffrey Braithwaite Natalie Taylor Despite the overwhelming interest in clinical genomics, uptake has been slow. Implementation science offers a systematic approach to reveal pathways to adoption and a theory informed approach to addressing barriers presented. Using case study methodology, we undertook 16 in-depth interviews with nongenetic medical specialists to identify barriers and enablers to the uptake of clinical genomics. Data collection and analysis was guided by two evidence-based behaviour change models: the Theoretical Domains Framework (TDF), and the Capability, Opportunity Motivation Behaviour model (COM-B). Our findings revealed the use of implementation science not only provided a theoretical structure to frame the study but also facilitated uncovering of traditionally difficult to access responses from participants, e.g., “safety in feeling vulnerable” (TDF code emotion/COM-B code motivation). The most challenging phase for participants was ensuring appropriate patients were offered genomic testing. There were several consistent TDF codes: professional identity, social influences, and environmental context and resources and COM-B codes opportunity and motivation, with others varying along the patient journey. We conclude that implementa...
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research