A novel hypoxia gene signature indicates prognosis and immune microenvironments characters in patients with hepatocellular carcinoma.

In conclusion, we identified a novel HCC-suitable 21-gene hypoxia signature that could be used to estimate the hypoxia exposure in HCC tissues and indicated prognosis and a series of important clinical features in HCCs. It may enable the development of personalized counselling or treatment strategies for HCC patients with different levels of hypoxia exposure.
PMID: 33616276 [PubMed - as supplied by publisher]

Source: J Cell Mol Med - February 22, 2021 Category: Molecular Biology Authors: Zhang Q, Qiao L, Liao J, Liu Q, Liu P, Liu L Tags: J Cell Mol Med Source Type: research