Centriolar defects, centrin 1 alterations, and FISH studies in human spermatozoa of a male partner of a couple that produces aneuploid embryos in natural and artificial fertilization

ConclusionA paternal contribution to sperm aneuploidies cannot be excluded since the patient ’s sperm showed altered morphology, immature centriolar adjunct, presence of evident distal centriole, scarce presence of centrin 1, and high aneuploidy frequency.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research