Evolution of IgA nephropathy in Singapore over four decades and a comparison of two cohorts from the first and fourth decade.

CONCLUSION: The Oxford MEST classification offers a robust and expressive classification for early and late disease progression with respect to the development of end-stage renal disease (ESRD). E and S seem to be indices of continuing disease activity with progressive glomerulosclerosis, probably still amenable to therapy, but T was a predictive indicator for those destined for ESRD and no longer amenable to therapy.
PMID: 33605873 [PubMed - as supplied by publisher]

Source: Clinical Nephrology - February 19, 2021 Category: Urology & Nephrology Authors: Woo KT, Chan CM, Foo M, Lim C, Choo J, Chin YM, Teng EWL, Mohamed Yusoff PA, Mok I, Kwek JL, Tan HZ, Loh AHL, Choong HL, Tan HK, Wong KS, Lee GSL, Lee E, Tan PH, Tan CS Tags: Clin Nephrol Source Type: research