Activation of WNT7b autocrine eases metastasis of colorectal cancer via epithelial to mesenchymal transition and predicts poor prognosis

Aberrant activation of the Wnt/ β-catenin signaling pathway is one of the most frequent abnormalities in human cancer, including colorectal cancer (CRC). Previous studies revealed pivotal functions of WNT famil...

Source: BMC Cancer - February 19, 2021 Category: Cancer & Oncology Authors: Shuai Jiang, Qiwen Li, Yimin Liu, Huimin Zhang, Qianyu Wang, Yu Chen, Xiaoyang Shi, Jun Li, Hailing Zhang, Yi Zhang, Dongqing Xia, Man Wu, Jiajia Lin, Chenglin Zhang, Suhua Pang, Jiamin Jiang & hellip; Tags: Research article Source Type: research