Determination of the initial minimum effective dose of 0.5% bupivacaine with 20mcg of fentanyl for an operative fixation of fractured neck of femur. A prospective, observational trial.

CONCLUSIONS: This study demonstrates that the placement of a spinal catheter allows for careful titration of local anaesthetic, enabling a reduction of the initial intrathecal dose of 0.5% isobaric bupivacaine below 0.4ml (2mg) and leading to a significant reduction of a dose required for the whole surgery when combined with an intrathecal opioid. PMID: 33591143 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33591143?dopt=Abstract

Source: Minerva Anestesiologica - February 18, 2021 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research