History of Mental Illness Associated With Earlier Signs of Aging

Individuals with a history mental illness are more likely to show signs of aging by age 45 —including cognitive decline and loss of motor coordination—than are people without such a history, according to areport published today inJAMA Psychiatry.This remained true even after controlling for a host of other factors that might explain early aging, such as poor health in childhood; being overweight; smoking; or a history of cancer, diabetes, or heart attack.“In this cohort study, a history of psychopathology was associated with accelerated aging at midlife, years before the typical onset of age-related diseases,” wrote lead author Jasmin Wertz, Ph.D., of Duke University and colleagues.Wertz and colleagues analyzed data from the Dunedin Multidisciplinary Health and Development Study, a study of 1,037 individuals (93% White) born between April 1, 1972, and March 31, 1973, in Dunedin, New Zealand. Participants were followed up to age 45. Of the original cohort, 997 were still alive at age 45 years, and 938 participated in the assessment at age 45 years.Interviews were conducted by health professionals using the Diagnostic Interview Schedule at ages 18, 21, 26, 32, 38, and 45 years to assess for symptoms of mental disorders, including attention-deficit/hyperactivity disorder, substance use disorder, generalized anxiety disorder, depression, obsessive-compulsive disorder, and schizophrenia. Based on these assessments, the researchers developed an overall score...
Source: Psychiatr News - Category: Psychiatry Tags: accelerated aging ADHD balance cognitive function depression hearing JAMA Psychiatry mental illness middle age schizophrenia vision Source Type: research

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