Autism Detection in Children by Combined Use of Gaze Preference and the M-CHAT-R in a Resource-Scarce Setting.

Autism Detection in Children by Combined Use of Gaze Preference and the M-CHAT-R in a Resource-Scarce Setting. J Autism Dev Disord. 2021 Feb 16;: Authors: Jensen K, Noazin S, Bitterfeld L, Carcelen A, Vargas-Cuentas NI, Hidalgo D, Valenzuela A, Roman-Gonzalez A, Krebs C, Clement V, Nolan C, Barrientos F, Mendoza AK, Noriega-Donis P, Palacios C, Ramirez A, Vittet M, Hafeez E, Torres-Viso M, Velarde M, Moulton LH, Powers MD, Gilman RH, Zimic M, Autism Working Group in Peru Abstract Most children with autism spectrum disorder (ASD), in resource-limited settings (RLS), are diagnosed after the age of four. Our work confirmed and extended results of Pierce that eye tracking could discriminate between typically developing (TD) children and those with ASD. We demonstrated the initial 15 s was at least as discriminating as the entire video. We evaluated the GP-MCHAT-R, which combines the first 15 s of manually-coded gaze preference (GP) video with M-CHAT-R results on 73 TD children and 28 children with ASD, 36-99 months of age. The GP-MCHAT-R (AUC = 0.89 (95%CI: 0.82-0.95)), performed significantly better than the MCHAT-R (AUC = 0.78 (95%CI: 0.71-0.85)) and gaze preference (AUC = 0.76 (95%CI: 0.64-0.88)) alone. This tool may enable early screening for ASD in RLS. PMID: 33591436 [PubMed - as supplied by publisher]
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research