Defining the index lesion for potential salvage partial or hemi-gland ablation after radiation therapy for localized prostate cancer.

CONCLUSIONS: In men with recurrent prostate cancer after radiotherapy, biopsy findings and MRI can be used to select index lesions potentially amenable for sPGA and can guide patient evaluation for inclusion in clinical trials of sPGA following radiation failure. Larger, prospective studies are required to evaluate both the role of MRI and clinical criteria in guiding focal salvage therapy and the effectiveness of this modality for radiorecurrent prostate cancer.
PMID: 33583697 [PubMed - as supplied by publisher]

Source: Urologic Oncology - February 11, 2021 Category: Urology & Nephrology Authors: Chesnut GT, Tin AL, Sivaraman A, Takeda T, Lee T, Fainberg J, Benfante N, Sjoberg DD, Vargas HA, Fine SW, Scardino PT, Eastham JA, Coleman JA, Touijer KA, Zelefsky MJ, Ehdaie B Tags: Urol Oncol Source Type: research