Development of a new barcode-based, multiplex-PCR, next-generation-sequencing assay and data processing and analytical pipeline for multiplicity of infection detection of Plasmodium falciparum

Simultaneous infection with multiple malaria parasite strains is common in high transmission areas. Quantifying the number of strains per host, or the multiplicity of infection (MOI), provides additional paras...

Source: Malaria Journal - February 16, 2021 Category: Infectious Diseases Authors: Rebecca M. Mitchell, Zhiyong Zhou, Mili Sheth, Sheila Sergent, Michael Frace, Vishal Nayak, Bin Hu, John Gimnig, Feiko ter Kuile, Kim Lindblade, Laurence Slutsker, Mary J. Hamel, Meghna Desai, Kephas Otieno, Simon Kariuki, Ymir Vigfusson & hellip; Tags: Research Source Type: research