Transient takotsubo syndrome and its recurrence: Why does it happen, why does it end, and why does it rarely reappear?

After reading a new, interesting, but limited report by Arcari et al. [1] on recurrent transient takotsubo syndrome (TTS; also known as takotsubo cardiomyopathy), I propose that we should abandon simple curiosity and face the persistent question, “What happened to my patients who had TTS?” This requires delving deeper into the pathophysiology of why the TTS initially occurred, why it stopped, and why it did not return for some time in most patients—especially given that TTS is supposedly a manifestation of common and persistent stresso rs, such as anxiety, catecholamines, adrenergic receptors, pain, depression, and cancer (factors that usually remain unchanged or worsen after TTS presentation), and that no effective anti-TTS medications or interventions are typically administered.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research