Dissecting Genetically Regulated Gene Expression in Major Depression

One of the major aims of complex trait and population genetics is to identify causal genes underlying disease onset and progression. Causal genes may then be used to identify disease mechanisms and subsequently inform the development of more effective drugs and treatment strategies. Large-scale genome-wide association studies (GWASs), which test millions of single nucleotide polymorphisms (SNPs) for an association with a disease outcome, have greatly expanded the discovery of genetic risk loci underlying complex diseases.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Early Career Investigator Commentary Source Type: research