Efficacy and Safety of 1% Progesterone Gel to the Forehead on Ocular Chronic Graft-versus-Host Disease

Chronic graft-versus-host disease (GVHD) is the leading cause of morbidity and mortality late after allogeneic hematopoietic stem cell transplant (allo-HSCT), which affects 30-70% of allo-HSCT survivors, with significant impact on quality of life.1,2 The eye is one of the major target organs affected by GVHD, occurring in greater than 50% of patients with chronic GVHD.3,4

Source: Biology of Blood and Marrow Transplantation - February 13, 2021 Category: Hematology Authors: Zhonghui K. Luo, Edgar A. Domenech-Estarellas, Amy Han, Do Lee, Ram Khatri, Jonathan L. Wahl, Corey Cutler, Philippe Armand, Joseph H. Antin, John Koreth, Mahasweta Gooptu, Edwin P. Alyea, Robert J. Soiffer, Vincent T. Ho Source Type: research