Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity

Epimedii Folium (EF) is commonly used for treating bone fractures and joint diseases, but the potential hepatotoxicity of EF limits its clinical application. Our previous study confirms that EF could lead to i...

Source: Cell Communication and Signaling - February 11, 2021 Category: Molecular Biology Authors: Yuan Gao, Guang Xu, Li Ma, Wei Shi, Zhilei Wang, Xiaoyan Zhan, Nan Qin, Tingting He, Yuming Guo, Ming Niu, Jiabo Wang, Zhaofang Bai and Xiaohe Xiao Tags: Research Source Type: research