Impact of total variation regularized expectation maximization reconstruction on the image quality of 68Ga-PSMA PET: a phantom and patient study.

CONCLUSIONS: TVREM improves lesion contrast and reduces image noise, which allows shorter acquisition with preserved image quality for PSMA PET/CT.
ADVANCES IN KNOWLEDGE: TVREM reconstruction with optimised penalisation factors can generate higher quality PSMA-PET images for prostate cancer diagnosis.
PMID: 33571001 [PubMed - as supplied by publisher]

Source: The British Journal of Radiology - February 11, 2021 Category: Radiology Authors: Yang FJ, Ai SY, Wu R, Lv Y, Xie HF, PhD YD, Meng QL, Wang F Tags: Br J Radiol Source Type: research