Comment on "Structural evidence for a dynamic metallocofactor during N2 reduction by Mo-nitrogenase"

Kang et al. (Reports, 19 June 2020, p. 1381) report a structure of the nitrogenase MoFe protein that is interpreted to indicate binding of N2 or an N2-derived species to the active-site FeMo cofactor. Independent refinement of the structure and consideration of biochemical evidence do not support this claim.

Source: ScienceNOW - February 11, 2021 Category: Science Authors: Peters, J. W., Einsle, O., Dean, D. R., DeBeer, S., Hoffman, B. M., Holland, P. L., Seefeldt, L. C. Tags: Biochemistry t-comment Source Type: news