Cervical ripening in prolonged pregnancies by silicone double balloon catheter < i > versus < /i > vaginal dinoprostone slow release system: The MAGPOP randomised controlled trial

by Caroline Diguisto, Am élie Le Gouge, Chloé Arthuis, Norbert Winer, Olivier Parant, Christophe Poncelet, Celine Chauleur, Jacob Hannigsberg, Guillaume Ducarme, Denis Gallot, Rene Gabriel, Raoul Desbriere, Gael Beucher, Cyrille Faraguet, Helene Isly, Patrick Rozenberg, Bruno Giraudeau, Franck Perrotin, for the Groupe de Recherche en Obstétrique et Gynécologie (GROG) BackgroundProlonged pregnancies are a frequent indication for induction of labour. When the cervix is unfavourable, cervical ripening before oxytocin administration is recommended to increase the likelihood of vaginal delivery, but no particular method is currently recommended for cervical ripening of prolonged pregnancies. This trial evaluates whether the use of mechanical cervical ripening with a silicone double balloon catheter for induction of labour in prolonged pregnancies reduces the cesarean section rate for nonreassuring fetal status compared with pharmacological cervical ripening by a vaginal pessary for the slow release of dinoprostone (prostaglandin E2). Methods and findingsThis is a multicentre, superiority, open-label, parallel-group, randomised controlled trial conducted in 15 French maternity units. Women with singleton pregnancies, a vertex presentation, ≥41+0 and ≤42+0 weeks’ gestation, a Bishop score
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research