Proton Pump Inhibitors, Associated Complications, and Alternative Therapies: A Shifting Risk Benefit Ratio.

CONCLUSIONS: Anti-reflux control can be safely achieved with either PPI or surgical options; however, the long-term side effects noted in the review such as increased risk of cardiovascular events, renal disease, and gut dysbiosis may suggest surgical anti-reflux control as a better long-term option. PMID: 33560890 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33560890?dopt=Abstract

Source: The American Surgeon - February 9, 2021 Category: Surgery Authors: Friedman AJ, Elseth AJ, Brockmeyer JR Tags: Am Surg Source Type: research