ROR γt licenses the differentiation and function of a unique subset of Tfh cells in response to immunogenic self‐DNA in systemic lupus erythematosus
ConclusionImmunogenic self ‐DNA instructs ICOS‐dispensable IL‐17+Tfh cells via ROR γt for IgG anti‐dsDNA response, serving as promising therapeutic targets for lupus patients.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Zhenke Wen,
Lin Xu,
Wei Xu,
Sidong Xiong Tags: FULL LENGTH Source Type: research