Pleuropulmonary Blastoma with Hotspot Mutations in RNase IIIb Domain of DICER 1: Clinicopathologic Study of 10 Cases in a Single-Institute Experience

Conclusions: Late detection of solid PPB is associated with poor prognosis. Considering the rarity of PPB disease and the importance ofDICER1 hotspot mutation in pathogenesis,DICER1 hotspot mutation testing and identification in the early cystic stage can improve patient outcomes.Pathobiology

https://www.karger.com/Article/FullText/512957

Source: Pathobiology - February 10, 2021 Category: Pathology Source Type: research