Sexuality and fertility related issues in women after allogeneic hematopoietic stem cell transplant

As probability of long term survival reaches 80% in patients who survive two years after allogeneic hematopoietic stem cell transplant (HSCT),1 management of late effects appears as a major concern. Among sequelae of HSCT, hypogonadism and infertility are important issues with a heavy impact on quality of life.2 These complications occur in most patients transplanted after myeloablative conditioning (MAC) regimens,3 but few data exist in the setting of reduced-intensity conditioning (RIC) regimens.

Source: Biology of Blood and Marrow Transplantation - February 5, 2021 Category: Hematology Authors: Nathalie Forgeard, Matthieu Jestin, Dominique Vexiau, Florian Chevillon, Elise Ricadat, R égis Peffault de Latour, Marie Robin, Flore Sicre de Fontbrune, Aliénor Xhaard, David Michonneau, Nicolas Boissel, Catherine Poirot, Nathalie Dhédin Source Type: research