Approach to screening for Familial Adenomatous Polyposis (FAP) in a cohort of 226 patients with Desmoid-type Fibromatosis (DF): experience of a specialist center in the UK

ConclusionsCTNNB1 ± APC testing and colonoscopy are useful tools for the screening of patients with DF.CTNNB1 molecular testing should be performed in all cases of newly diagnosed DF. NegativeCTNNB1 results, alongside clinical assessment, should promptAPC testing and/or colonoscopy.
Source: Familial Cancer - Category: Cancer & Oncology Source Type: research