Iron deficiency impacts prognosis but less exercise capacity in heart failure with preserved ejection fraction

ConclusionsHeart failure with preserved ejection fraction patients with ID have a worse prognosis and impaired exercise capacity compared with those without ID. However, although a trend was observed, after multivariable correction ID was no longer significantly associated with a reduced exercise capacity. This reflects that impaired exercise capacity in HFpEF is complex and seems multifactorial. Interestingly, pulmonary hypertension was an independent predictor of both ID and exercise capacity.

Source: ESC Heart Failure - February 1, 2021 Category: Cardiology Authors: Arantxa Barandiar án Aizpurua, Sandra Sanders‐van Wijk, Hans‐Peter Brunner‐La Rocca, Michiel T.H.M. Henkens, Jerremy Weerts, Mireille H.A. Spanjers, Christian Knackstedt, Vanessa P.M. Empel Tags: Original Research Article Source Type: research