Association of depressive symptoms with postoperative delirium and CSF biomarkers for Alzheimer's disease among hip fracture patients

Delirium is a syndrome defined by acute changes in attention and cognition 1 that commonly occurs in hospitalized older adults after acute illness or surgery. Delirium is associated with increased morbidity and mortality, longer hospital stays, as well as physical and cognitive decline 2. The estimated annual health care costs associated with delirium and its downstream effects are over $164 billion dollars in the United States.3 Although delirium occurs in various clinical settings, the risk is especially high among older adults undergoing hip fracture surgery, with incidences ranging from 13 % to 56 % 4.

Source: The American Journal of Geriatric Psychiatry - February 3, 2021 Category: Geriatrics Authors: Carol K Chan, Frederick E Sieber, Kaj Blennow, Sharon K Inouye, Geoffrey Kahn, Jeannie-Marie S Leoutsakos, Edward R Marcantonio, Karin J Neufeld, Paul B Rosenberg, Nae-Yuh Wang, Henrik Zetterberg, Constantine G Lyketsos, Esther S Oh Tags: Regular Research Article Source Type: research