Whole Blood Thrombin Generation in Severely Injured Patients Requiring Massive Transfusion

Whole blood was collected from trauma activation patients at a single trauma center. Whole blood thrombin generation (TG) was measured. Whole blood TG was depressed in patients with shock and it effectively predicted massive transfusion, challenging the prevailing bias that all trauma patients present with elevated TG.

Source: Journal of the American College of Surgeons - February 3, 2021 Category: Surgery Authors: Julia R. Coleman, Ernest E. Moore, Jason M. Samuels, Mitchell J. Cohen, Christopher C. Silliman, Arsen Ghasabyan, James Chandler, Saulius Butenas Tags: Original Scientific Article Source Type: research