Current smoking negatively affects the response to methotrexate in RA in a dose-responsive way, independently of concomitant prednisone use.

CONCLUSION: Current smoking in early RA patients significantly reduces the clinical effect of an MTX-based strategy, independent of whether concomitant prednisone is used or not. This effect is dose dependent. PMID: 33526623 [PubMed - as supplied by publisher]
Source: Journal of Rheumatology - Category: Rheumatology Tags: J Rheumatol Source Type: research