The association of perinatal and clinical factors with outcomes in infants with gastroschisis —a retrospective multicenter study in Finland

Conclusion: The risk of death is increased in newborns with gastroschisis who have liver herniation, pulmonary hypoplasia, abdominal compartment syndrome, relaparotomy for perforation or necrosis, or central line –associated sepsis. Special care should be taken to minimize the risk of central line sepsis in the clinical setting.What is known:•Gastroschisis is a relatively rare congenital anomaly of the abdominal wall and its incidence is increasing.•Complex gastroschisis has been reported to increase risk of mortality and complications.What is new:•Central line sepsis was found to be independently associated with mortality in gastroschisis patients.•Liver herniation was also significantly associated with mortality.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research