Increased multiple sclerosis disease activity in patients transitioned from fingolimod to dimethyl fumarate: a case series

Fingolimod is a S1P1 receptor modulator that prevents activated lymphocyte egress from lymphoid tissues causing lymphopenia, mainly affecting CD4+ T lymphocytes. Withdrawal from fingolimod can be followed by seve...

Source: BMC Neurology - February 2, 2021 Category: Neurology Authors: Silvia Delgado, Jeffrey Hernandez, Leticia Tornes and Kottil Rammohan Tags: Case report Source Type: research