Study identifies noncoding RNA involved in immune response and sepsis

(University of California - Santa Cruz) When the body's immune response to an infection gets out of control, the result can be sepsis, a life-threatening condition in which an overwhelming inflammatory response can lead rapidly to failure of multiple organs and death. In a new study, researchers at UC Santa Cruz have identified a long noncoding RNA (lncRNA) molecule that regulates the expression of pro-inflammatory genes in immune system cells called macrophages and affects the susceptibility of mice to septic shock.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news