COVID-19 Therapeutic Alert - Antimicrobials (azithromycin and doxycycline) Not Beneficial in the Management of COVID-19 (SARS-CoV-2) Positive Patients, MHRA

Azithromycin and doxycycline should NOT be used in the management of confirmed or suspected COVID-19 infection within primary care, and azithromycin should not be used in hospitalised patients, unless there are additional indications for which use remains appropriate.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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AbstractCoronavirus disease 2019 (COVID-19) accounts for over 180,000 deaths in the USA. Although COVID-19 affects all racial ethnicities, non-Hispanic Blacks have the highest mortality rates. Evidence continues to emerge, linking the disproportion of contagion and mortality from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a result of adverse social determinants of health. Yet, genetic predisposition may also play a credible role in disease transmission. SARS-CoV-2 enters cells by interaction between SARS-CoV-2 spike protein and the receptor molecule angiotensin converting enzyme 2 (ACE2) expressed on the...
Source: Journal of Racial and Ethnic Health Disparities - Category: International Medicine & Public Health Source Type: research
Conditions:   Covid19;   SARS-CoV 2 Infection Intervention:   Drug: Carrageenan nasal spray and 1% PVP- mouthwash and gargle Sponsor:   National Taiwan University Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   COVID19 Intervention:   Biological: Recombinant SARS-CoV-2 Fusion Protein Vaccine Sponsors:   Livzon Pharmaceutical Group Inc.;   Guangdong Center for Disease Prevention and Control;   Simoon Record Pharma Information Consulting Co., Ltd. Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
(Natural News) Polymerase chain reaction (PCR) tests for the Wuhan coronavirus (COVID-19) are part of many countries’ response to the pandemic. However, these tests do not allow people to know what particular SARS-CoV-2 variant is behind their sickness. Many patients have thus claimed that laboratories refusing to disclose their complete COVID-19 test results violate their...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
In The Lancet Psychiatry, Dana Tzur Bitan and colleagues present the results of the first longitudinal study assessing COVID-19 outcomes before and after vaccination in a cohort of over 25 000 people with schizophrenia and an equally large sample of matched controls in Israel. Particular strengths of this study are the impressive and well-characterised dataset, and the longitudinal design, allowing exploration of dynamic trends over the course of the first year of the COVID-19 pandemic. From a policy perspective, Israel, where all citizens aged 16 and older gained full access to SARS-CoV-2 vaccination as early as January, ...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Iran J Microbiol. 2021 Jun;13(3):381-388. doi: 10.18502/ijm.v13i3.6401.ABSTRACTBACKGROUND AND OBJECTIVES: In 2020 the whole world is experiencing a pandemic condition due to infection with the SARS-CoV-2 virus which can cause the COVID-19 disease. This condition results in "Panic Buying", because everyone tries to avoid the spread and transmission of the COVID-19 disease by doing various ways, one of which is by taking additional supplements such as vitamin C and probiotic supplements.MATERIALS AND METHODS: The materials used were mice Mus musculus male DDY strain aged 1-2 months. Probiotic supplement Lactobacill...
Source: Iranian Journal of Microbiology - Category: Microbiology Authors: Source Type: research
CONCLUSION: The analysis of SARS-CoV-2 from WGS Indonesia showed a high genetic variation. The diversity in SARS-CoV-2 may epidemiologically enhance virulence and transmission of this virus. The prevalence of D614G over the time in different locations, indicating that changes in this mutation may related to host infection and the viral transmission. However, some mutations that have been reported in this study were not eligible for the most stable conformation.PMID:34540148 | PMC:PMC8408024 | DOI:10.18502/ijm.v13i2.5973
Source: Iranian Journal of Microbiology - Category: Microbiology Authors: Source Type: research
CONCLUSION: Gastrointestinal ischemia represents a rare manifestation of COVID-19. A high index of suspicion should lead to investigate this complication by CT scan, in the attempt to reduce its high mortality rate. Histology shows atypical feature of ischemia with important endotheliitis, probably linked to thrombotic microangiopathies.PMID:34539144 | PMC:PMC8409161 | DOI:10.3748/wjg.v27.i32.5448
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
We report the cases of ten patients hospitalized in Rehabilitation Units after COVID-19, who presented severe focal motor involvement. Electrophysiological investigations revealed focal sensory-motor neuropathies, atypical for many aspects: bilaterality, location and contemporary involvement of different nervous districts. We speculate that their pathogenesis is possibly related to prolonged abnormal postures maintained during hospitalization in Intensive Care Unit, virus neurotropism and thrombotic vascular damage involving vasa nervorum.CLINICAL REHABILITATION IMPACT: Motor neuropathies could induce severe disability and...
Source: European Journal of Physical and Rehabilitation Medicine - Category: Rehabilitation Authors: Source Type: research
CONCLUSION: Gastrointestinal ischemia represents a rare manifestation of COVID-19. A high index of suspicion should lead to investigate this complication by CT scan, in the attempt to reduce its high mortality rate. Histology shows atypical feature of ischemia with important endotheliitis, probably linked to thrombotic microangiopathies.PMID:34539144 | PMC:PMC8409161 | DOI:10.3748/wjg.v27.i32.5448
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research
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