Quantifying MRI T1 relaxation in flowing blood: implications for arterial input function measurement in DCE-MRI.

CONCLUSIONS: The T1 measurement of flowing blood using standard DCE- MRI sequences are subject to large measurement errors which are non-linear in relation to flow velocity.
ADVANCES IN KNOWLEDGE: This work qualitatively and quantitatively demonstrates the difficulties of accurately measuring the T1 of flowing blood using DCE-MRI over a wide range of physiologically realistic flow velocities and pulsatilities. Sources of error are identified and proposals made to reduce these.
PMID: 33507818 [PubMed - as supplied by publisher]

Source: The British Journal of Radiology - January 28, 2021 Category: Radiology Authors: Gwilliam MN, Collins DJ, Leach MO, Orton MR Tags: Br J Radiol Source Type: research