Characterization of an expanded IL-10-producing-suppressive T cell population associated with immune tolerance.

In conclusion, expanded TIGIT+CD39+GITR+Foxp3-CD4+ T cells shifted from an effector Th1 to IL-10-producing-suppressor T cell phenotype, which may promote an immune-tolerant state. PMID: 33504740 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33504740?dopt=Abstract

Source: Biological and Pharmaceutical Bulletin - January 26, 2021 Category: Drugs & Pharmacology Authors: Yoshida Y, Mikami N, Nakanishi Y, Saimoto M, Nagaike A, Shimono H, Nakano S, Tsuji T, Kohno T Tags: Biol Pharm Bull Source Type: research